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AmericanSociologicalReview, v. 48, p. 147 160, April, 1983. Disponvel em: . Acesso em 15 de outubro de 2013. DIMAGGIO, P.


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An important consideration for a new endpoint is its impact on study sample size. For a given NI margin, utilizing a risk difference analysis approach, the sample size decreases as the endpoint rate decreases from 50%. However, if the endpoint rate drops below 15%, the potential for loss of clinically acceptable efficacy with a 10% NI margin may be judged too great, such that a smaller NI margin is appropriate. If a fixed NI margin of 10% is not supportable, then either a lower fixed NI margin eg, 7% or an odds ratio analysis approach is required . Either approach results in an increased study sample size. For example, a trial design assuming an ACM rate of 15% and a 10% NI margin requires 402 patients for the primary analysis.



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The bottom line is this: All the different ways that we examined this issue pointed to the same conclusion, said M. Rebecca Kilburn, a senior economist at RAND and a coauthor of the study. What's exciting about this is that we're getting to the point where policymakers have a lot of evidence that well implemented early childhood programs are a good investment. San Felipe Pueblo is a bend in the road about 25 miles north of Albuquerque, New Mexico, a scattering of homes on the banks of the Rio Grande. It's an old Native American farming village, known for its annual corn dance, where bread baking in traditional backyard ovens sweetens the air. Its 3,500 residents still grow up speaking the indigenous Keresan language. It has fought hard to preserve its traditions in the face of poverty and economic isolation. Like disadvantaged communities from inner city Detroit to rural New York, it has focused especially on raising up its youngest generation. It has a small team of family health educators, drawn from the pueblo itself, who visit new mothers in their homes and offer them support and guidance in their own language. The program's name, Project KEVA, stands for Katishtya Eh wahs Valued Always in Keresan: San Felipe Kids Are Valued Always. Its symbol is a butterfly.



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sabap kalimo ko ged sakanin, ininggey ko pagkababy ko sa lakanin. Agid di kana bo nakaysa nami ningula, aden pan tinumondog, Taman sa nakowma gey na natawang ko, magingey ako!Dala ko gidtalo sa uyab ko ka magilek ko na ipawa nin bo. Sabap ka to ba e una na nanggula salaki di ko katawan nin anggolan ko. minuli ko salakami, san ko pan sa lanan pambatad ko den sa ginawa ko nin adtalon ko kani ina ko anggo kani ama ko anggo si ina, minu silan sa Davao ka nagbakasyon. Kaka ko bo mama o swaley nami. tok. tokoh sister,why your here?my brother askedahh. where they are?repliedTheyre not here, they went to Davao for vacationmy brother saidI keep on walking leading the same way and then I called my brother and I tolled everything what happen till my parents came back and I hug them while my tears are keep on moving out . Ma, I have important thing to tell you I saidWhat is it Heja?mama askedMa I am pregnant and please forgive me!I tolled herWhat?What was that?Please tell me hija that twasnt true, please tell me that you are lying my father insistedI was too speechless, meanwhile he stand up and went to his room and I dont know what to do. My mother saidYou must to go to Aleyas roommy sister and I dont to see you anymore And I went to the said room with my brother. Sis, for the meantime you must to stay at our grand mas house and dont come back here till they dont forgive you my brother saidI kept all my things ang immediately I went to my grandmas house.



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